| Characteristic | Details |
|---|---|
| Brand Name | Revatio |
| Mechanism of Action | PDE5 Inhibitor |
| Indications | Pulmonary Arterial Hypertension (PAH) |
| Pregnancy | Consult with healthcare provider |
| Adverse Effects | Headache, Dizziness, Visual Disturbances |
| Visit Revatio Site | |
Mechanism of Action of Revatio
The primary compound in Revatio, sildenafil, serves as a phosphodiesterase type 5 (PDE5) inhibitor. It amplifies the effects of nitric oxide. This results in smooth muscle relaxation in the pulmonary vasculature. Such relaxation leads to decreased pulmonary arterial pressure. The effect promotes improved hemodynamics. The efficacy of Revatio is attributed to this mechanism. The medication prolongs the life of cyclic guanosine monophosphate (cGMP). Elevated cGMP leads to vasodilation. Consequently, patients experience relief from symptoms of pulmonary hypertension. Revatio’s action is specific to PDE5, located predominantly in the lungs.
Indications for Revatio Usage
Revatio is primarily indicated for the treatment of pulmonary arterial hypertension (PAH). PAH patients often suffer from increased blood pressure within the arteries of the lungs. The condition leads to difficulty in breathing and reduced exercise capacity. Clinical trials have shown Revatio to be effective in improving exercise ability and delaying clinical worsening. It is especially beneficial in adults with WHO Group I PAH. Healthcare providers may also consider Revatio in pediatric cases, though this requires careful assessment.
Pregnancy and Breastfeeding Considerations
The administration of Revatio during pregnancy requires careful deliberation. Healthcare professionals should assess potential benefits against risks. There are no adequate studies in pregnant women. Therefore, sildenafil should be used during pregnancy only if clearly needed. For breastfeeding mothers, information is limited. It is unknown if sildenafil or its metabolites pass into human milk. Caution is advised when prescribing to nursing mothers. Consultation with healthcare professionals is essential to make informed decisions. Detailed information can be accessed from FDA resources.
Adverse Effects of Revatio
Like all medications, Revatio may cause side effects. The most commonly reported are headache, dizziness, and visual disturbances. Patients may also experience flushing or dyspepsia. Severe adverse reactions include sudden loss of vision or hearing. These require immediate medical attention. The occurrence of adverse effects varies among individuals. It is crucial for patients to communicate with their healthcare provider. Monitoring and reporting any unexpected reactions can help in managing side effects effectively.
Availability of Revatio Online
Revatio is accessible through online pharmacies. Patients should exercise caution when purchasing medications online. Ensuring the legitimacy of the pharmacy is vital. Counterfeit drugs pose serious health risks. Verification of online pharmacy credentials is recommended. Safe purchasing practices involve confirming the authenticity of the medication. Consultation with healthcare providers before purchasing online can ensure safety. A reputable source ensures the medication meets safety standards. Accessing reliable sources is essential for patient safety and health.
| Side Effect | Frequency |
|---|---|
| Headache | Common |
| Dizziness | Common |
| Visual Disturbances | Less Common |
- Consult healthcare professionals before starting Revatio.
- Report any adverse effects immediately.
- Verify online pharmacies for authenticity.
Data origin:
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